Hint: One of the few Americans to have a chess-opening-line named after him; Which commences on the 4th move.
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The correct answer to this posed question, is being given in the spirit of the Biblical passage, from "Proverbs"; Ie.- 'The rain falls on the just and unjust'.. {generally speaking, of course}.
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The 'Kopec System'; For which IM Danny Kopec has deservedly received credit, due to his tireless experimentation; Is another alternative for White, to the Open Sicilian.
 
It arises after 1 e4 c5 2 Nf3 d6 {the most feared move, heading to the Najdorf or the Dragon}, 3 c3 Nf6 {the attack on the e-pawn stops White from getting in d2-d4 as in the 2 c3 Sicilian}; And then Kopec's championed move is 4. Bd3. The idea is to later drop back to c2 and then play for d2-d4 as in a Closed Ruy Lopez; Or maintain the 'closed' pawn configuration {of, pawn on 'd3'}, indefinitely.